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KMID : 0387920080190020178
Korean Journal of Cytopathology
2008 Volume.19 No. 2 p.178 ~ p.182
Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytology in the Diagnosis of a Gastrointestinal Stromal Tumor of the Stomach -A Case Report -
Kim Lucia

Choi Suk-Jin
Han Jee-Young
Kim Joon-Mee
Chu Young-Chae
Park In-Suh
Kim Hyung-Gil
Kim Sun-Hee
Lee Don-Haeng
Abstract
We report here a case of a gastrointestinal stromal tumor (GIST) in the stomach that was diagnosed by endoscopic ultrasound-guided fine needle aspiration cytology (EUS-FNA). A 67 year old male patient underwent regular check-ups for five years due to the presence of a submucosal tumor that was found in the fundus of the stomach incidentally. EUS-FNA was performed to evaluate the tumor, which had increased in size from 1 cm to 2.8cm. A cytologic smear revealed cohesive sheets or clusters of spindle cells with elongated nuclei. Immunohistochemical staining revealed a strong positive reaction for c-kit and CD34, without any reaction for smooth muscle actin and Ki-67. Therefore, a diagnosis of GIST was made.
KEYWORD
Gastrointestinal stromal tumor, Endoscopy, Ultrasound-guided fine needle aspiration cytology, Immunohistochemistry
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